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AI and Biosecurity

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AI and Biosecurity

Measuring Mid-2025 LLM-Assistance on Novice Performance in Biology

February 2026
Research Paper
Shen Zhou Hong, Alex Kleinman, Alyssa Mathiowetz, Adam Howes, Julian Cohen, Suveer Ganta, Alex Letizia, Dora Liao, Deepika Pahari, Xavier Roberts-Gaal, Luca Righetti, Joe Torres

Large language models (LLMs) perform strongly on biological benchmarks, raising concerns that they may help novice actors acquire.

Threat Modeling

Dual-Use AI Capabilities and the Risk of Bioterrorism

December 2025
GovAI Report
Luca Righetti

Several frontier AI companies test their AI systems for dual-use biological capabilities that might be misused by...

AI and Biosecurity

Forecasting LLM-Enabled Biorisk and the Efficacy of Safeguards

July 2025
Bridget Williams, Luca Righetti, Josh Rosenberg, Rebecca Ceppas de Castro, Otto Kuusela, Rhiannon Britt, Emily Soice, Alvaro Morales, Jon Sanders, Seth Donoughe, James Black, Ezra Karger, Philip E. Tetlock

Capabilities of large language models (LLMs) on several biological benchmarks have prompted excitement about their usefulness for...